200937-17-3 Boc-D-Leu-OH•H2O

Ho sibolloa ha Biochemistry le Lithethefatsi:
Joaloka motsoako oa amino acid, Boc-D-Leu-OH·H2O e bapala karolo ea bohlokoa ho kopanyeng li-peptide le liprotheine tse sebetsang ka bioloji.Liphetoho tsa lik'hemik'hale tsa motsoako ona li ka lebisa ho nts'etsopele ea lithethefatsi tse ncha kapa likhetho tsa lithethefatsi bakeng sa ho phekola mafu a sa tšoaneng.Thepa e ikhethang ea D-leucine e ka fana ka mesebetsi e ikhethileng ea tlhaho ho li-peptide tse entsoeng kapa liprotheine.
Peptide Synthesis:
Ka mokhoa o tiileng oa peptide synthesis, Boc-D-Leu-OH · H2O ke monoma ea bohlokoa ea amino acid.Sehlopha sa eona sa tšireletso sa N-terminal Boc se lumella amino acid ligation le ts'ireletso tlas'a maemo a bonolo, e nolofalletsang ho kopanya liketane tsa peptide ka tatellano le mesebetsi e itseng.
Patlisiso ea Lab:
Boc-D-Leu-OH·H2O hangata e sebelisoa lithutong tsa peptide synthesis le protheine ea sebopeho.Ka ho e kopanya le li-monomers tse ling tsa amino acid, tatellano e fapaneng ea peptide e ka etsoa ho batlisisa litšebelisano tsa protheine le protheine-ligand, hammoho le ts'ebetso ea protheine le mekhoa ea taolo.
Li-reagents tsa Peptide le Lisebelisoa tsa Synthetic:
Boc-D-Leu-OH · H2O e ka sebetsa e le moemeli ea sireletsang kapa e fokotsang motsoako oa peptide, ho ntlafatsa katleho le bohloeki ba ts'ebetso ea peptide synthesis.Ntle le moo, e ka sebelisoa e le sesebelisoa sa peptide bakeng sa ho ngola peptide, ho e fetola le ho lemoha.
Asymmetric Synthesis:
Ka lebaka la tlhaho ea chiral ea D-leucine, Boc-D-Leu-OH·H2O e na le lisebelisoa tse ka bang teng ho asymmetric synthesis.Ka ho e kopanya le limolek'hule tse ling tsa chiral, li-peptide le liprotheine tse nang le li-stereoconfigurations tse khethehileng li ka kopanngoa ho ithuta phello ea chirality mesebetsing ea likokoana-hloko.