China 22254-24-6 8-Isopropylatropinium bromide Moetsi le Fektheri |Jiayinglai

22254-24-6 8-Isopropylatropinium bromide

Tlhaloso e Khutšoanyane:

Ponahalo	Likristale tse tšoeu ho isa ho tse tšoeu kapa phofo ea crystalline.
MF	Setšoantšo sa C20H30BrNO3
MW	412.37
Bohloeki	98+

Re romelle lengolo-tsoibila

Lintlha tsa Sehlahisoa

Boemo ba lipalangoang&mokhoa oa ho romella o khothalelitsoeng:
ka moya, ka lewatle kapa ka polelo

Boemo ba polokelo:
Boemo bo sa tsitsang, Mocheso oa Kamore

Bonyane Bonyane ba Odara:
Puisano

Setifikeiti:
COA, HPLC, GC, HNMR, Assay, Water Content(KF), TLC e teng

Litlhaloso tse tšoanang

8-Azoniabicyclo[3.2.1]octane, 3-(3-hydroxy-1-oxo-2-phenylpropoxy) -8-methyl-8-(1-methylethyl)-, (endo,syn)-, bromide;
8-Isopropylatropinium bromide;
3-alpha-Hydroxy-8-isopropyl-1-alpha-H, 5-alpha-H-tropanium bromide (±) -tropate;
2-Methyl-2- [(piperidinomethyl) thio] propionic acid;
8-Azoniabicyclo[3.2.1]octane, 3-(3-hydroxy-1-oxo-2-phenylpropoxy) -8-methyl-8-(1-methylethyl)-, bromide, (endo,syn)-;8- Azoniabicyclo[3.2.1]octane, 3-(3-hydroxy-1-oxo-2-phenylpropoxy)-8-methyl-8-(1-methylethyl)-, bromide, (endo,syn)-(+-)- ;8-Isopropylatropinium bromide (6CI, 7CI);
Atrovent forte

Ho paka ka hare

Hangata li sebelisoa ho paka phofo.'Me li ka thibela khanya ea letsatsi le metsi hore li se ke tsa senyeha.

ho phuthela ka ntle

Lebokose le thata le ka sireletsa lihlahisoa tsa hau ho senya le ho koloba.

Lisebelisoa

Ipratropium bromide e boetse e tsejoa e le Haizhupanidine, isopropyl atropine, isopropyl scopolamine, isopropyl atropine, ipratropine bromide, isopropyl atropine bromide, ipratropine bromide, ipratropium bromide, le ipratropium bromide.Ke phofo e tšoeu ea kristale e nang le tatso e bohloko.Sebaka se qhibilihang ke 232 ℃-233 ℃.E qhibiliha ka metsing, e qhibiliha hanyenyane ka har'a ethanol, ha e qhibilihe ka har'a metsoako e meng ea tlhaho.Lebitso la lik'hemik'hale: Brominated α- (hydroxymethyl) -phenylacetic acid - 8-methyl-8-isopropyl - azocyclic [3,2,1] -3-octyl ester.Ke sethethefatsi sa anticholinergic, se nang le phello e matla ea ho phomola mesifa ea bronchial boreleli le phello ea antiasthmatic ho mafu a sa foleng a thibelang matšoafo.Phello ea eona e totobetse, phello e potlakileng le nako e telele.Ipratropium bromide e boetse e laola ho ntšoa ha litšoelesa tsa mucus le ho ntlafatsa motsamao oa ciliary, kahoo e fokotsa tšitiso ea sekhohlela ho ntlafatsa moea.Ho sa le joalo, ho fokotseha ha sekhohlela ho boetse ho kokobetsa bronchospasm e bakoang ke ho teneha ha bronchi.Bakeng sa thibelo le kalafo ea asthma ea bronchial le asthmatic e sa foleng ea bronchitis, haholo-holo ho bakuli ba sa khoneng ho mamella ts'ebeliso ea ho thothomela ha mesifa ea β-agonist, tachycardia.Sehlahisoa sena se ka sebelisoa hammoho le beta-agonists ho ntlafatsa katleho ea e mong le e mong, joalo ka ha e kopana le finoterol ho etsa aerosol (BERODU -- AL) bakeng sa asthma, bronchitis e sa foleng le emphysema.Ha ho bapisoa le li-stimulants tsa β-adrenergic receptor (mohlala, isopropyl epinephrine), sehlahisoa sena se na le litla-morao tse fokolang tsa pelo, 'me ha se bapisoa le li-stimulants tsa β2-receptor (mohlala, Suquanling), sehlahisoa sena se na le matla a ho laola molumo oa phlegm.
Fafatsa ka ho hema.40 ~ 80μg hang, 2 ~ makhetlo a 4 ka letsatsi.Ha u sebelisa, qala ka ho tlosa sekoahelo sa khetla, beha sekoahelo sa khetla holim'a nozzle, fetola botlolo fatše, e na le khetla ea sekoahelo ka hanong, lebisa 'metsong, monya khase ka nako e le 'ngoe, tobetsa molomo. holim'a valve, kenya mokelikeli, tšoara moea oa hau nakoana.Pheta snap e ka holimo hang ha ho hlokahala.Aerosol: tharollo ea 0.025%.Letlapa: 10mg/tablet.
Chefo e matla ea anticholinergic e ka phekoloa ka li-inhibitors tsa cholinesterase.
Litlamorao tse mpe tsa ipratropium bromide li tšoana le atropine, e ka bakang ho otla ha pelo, hlooho, ho tsekela, ho tšoha, ho nyekeloa ke pelo, ho hlatsa, bohloko ba ka mpeng, ho thothomela, pono e lerootho, molomo o omileng, khohlela, dysuria, ho mpefala ha matšoao a ho hema le lekhopho.
Ipratropium bromide ke mohanyetsi oa muscarinic, bronchodilator, le letsoai la isopropyl la AtropineN.
Ipratropiumbromide le Formoterol li kopantsoe karolo e 'ngoe ho sireletsa matšoafo ho tsoa ho ruruha ho sa foleng le ho atolosa matšoafo, ho fokotsa li-neutrophils ka ho thibela mosebetsi ka MMP-9.Ipratropiumbromide(1nM) e ile ea eketsa haholo calcium bromide, ea fokotsa ho hasana ho ea pele le ho eketsa ho tlama ha annexin-V.Ka mor'a phekolo ea Ipratropiumbromide, hemolysis e ile ea eketseha hanyenyane empa haholo.Ipratropiumbromide e baka ho ipolaea ha lisele tse khubelu tsa mali kapa eryptosis, haholo-holo ka lebaka la khalsiamo e susumetsang.
Ipratropium phofo e omeletseng ea phofshoana (DPI) e ne e le bronchodilator e sebetsang ho lipere tse phomotseng ka tekanyo ea 2400 mg / pere, e nang le phello e fokolang holim'a maemo a holimo a moea nakong ea ho hlaphoheloa.Likhotong tse tšoaroang ke cadmium, Ipratropium e ile ea fokotsa haholo phallo ea lisele tsa ho ruruha tsa parenchymal 'me ea bona maqeba a mangata a amanang le matšoafo.Ipratropium e sireletsa karoloana ea matšoafo ho tsoa ho ruruha ka ho fokotsa ho kenella ha neutrophil.Ka har'a mesifa e boreleli ea kolobe ea Guinea, Ipratropium ke mohanyetsi ea thibelang mothapo oa pele oa muscarinic inhibitory oa methapo ea parasympathetic ea matšoafo.Ipratropium e boetse e bontšitsoe hore ke mohanyetsi ea matla ka mor'a ho tlama li-receptor tsa muscarinic inhibitory.Ipratropium e fokotsa liphetoho tse ngata khatellong ea sefuba 'me e eketsa ho lumellana ho matla (Cdyn) ho phefumoloha ha metsi (incremental Pplmax) le pulmonary resistance (RL) ho lipere.

E fetileng: 171596-29-5 Tadalafil

E 'ngoe: 1001202-16-9 Fmoc-Gly-Gly-Gly-Gly-OH

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