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122235-70-5 BOC-DAP(FMOC)-OH

122235-70-5 BOC-DAP(FMOC)-OH

Tlhaloso e Khutšoanyane:

Ponahalo Phofo e tšoeu ho isa ho Off-White
MF C23H26N2O6
MW 426.46
Bohloeki 98+


Lintlha tsa Sehlahisoa

Boemo ba lipalangoang&mokhoa oa ho romella o khothalelitsoeng:
ka moya, ka lewatle kapa ka polelo

Boemo ba polokelo:
2-8°C

Bonyane Bonyane ba Odara:
Puisano

Setifikeiti:
COA, HPLC, GC, HNMR, Assay, Water Content(KF), TLC e teng

D-Ls(tfa)-NCA (2)

Litlhaloso tse tšoanang

Boc-3-(Fmoc-amino)-L-alanine,Nα-Boc-Nβ-Fmoc-L-2,3-diaminopropionicacid;

NALPHA-tert-Butoxycarbonyl-NB-9-fluorenylmethoxycarbonyl-L-2,3-diaminopropi;

N-.ALPHA.-BOC-N-.BETA.-FMOC-L-2,3-DIAMIOPROPIONICACID;

N-Boc-N-Fmoc-(S) -2,3-diaminopropionicacid;

N-α-Boc-N-β-Fmoc-L-2,3-diamiopropionicacid;

(S) -2,3-Diaminopropanoicacid,N2-BOC,N3-FMOCsireletsehile;

3-[(9H-Fluoren-9-ylmethoxycarbonyl)amino]-L-alanine,N-BOCSireletsehile;

Boc-Dapa(FMoc)-OH

Ho paka ka hare

Hangata li sebelisoa ho paka phofo.'Me li ka thibela khanya ea letsatsi le metsi hore li se ke tsa senyeha.

Ho paka ka hare 2
Ho paka ka hare 1
Ho paka ka hare 3

ho phuthela ka ntle

Lebokose le thata le ka sireletsa lihlahisoa tsa hau ho senya le ho koloba.

Ho paka ka ntle 3
Ho paka ka ntle 2
Ho paka ka ntle 1

Lisebelisoa

Li-amino acid tse sireletsang habeli haholo-holo li kenyelletsa D-lys-OH e nang le lihlopha tsa amino tse mahlakoreng le ketane e nang le ketane.pho potoloha ha L-Rag-OH.Bakeng sa sehlopha sa AA-amin, leano la tšireletso la FMOC le ntse le amoheloa, 'me malome oa bobeli oa carbonate tse peli o sebelisoa ketane ea mahlakoreng.Tibon e kenngoa sehlopheng sa liphaephe tsa oxygenyl ho sireletsa Fu Fu 5 ~ Sulfidal ho sireletsa.Hobane ho na le mehato e mengata ea ho kopanya li-amino acid tsena tse peli, karabelo ea mantlha karabong ea mantlhasteps etsa liteko tsa ho ntlafatsa ntho e le 'ngoe.Tšireletso ea D-LYS-OH haholo-holo e nahana ka nako e amang moloko oa koporo e lekanangthemocheso, le nako ea ho tlosa koporo.Tšireletso ea L-Rag-OH haholo-holo e nahana ka ho lokisetsa Z-RG-OH. Ka nako eo, mocheso oa ZL-Rag (PBF) -OH selikalikoe sa letsoai la ammonia, hammoho le palo ea li-catalyst ha hydrogen e entsoe ka Z,tkhatello ea hae, mocheso le nako ea karabelo li fumane tlhahiso e ntle ka liteko tsa optimization.

Nakong ea ts'ebetso ea karabelo, ts'ebetso ea ho lemoha ha T.C e amoheloa haholo-holo, 'me maemo a crystallization a sehlahisoa a ntlafatsoa.

Bohloeki ba sehlahisoa bo ne bo lekantsoe ka chromatography ea metsi e sebetsang hantle haholo, 'me bohloeki ba sehlahisoa bo fihlile ho feta 95.0%.Ho phaella ho matšoao a tloaelehileng a 'mele kamehla, hapeiho kenyeletsoa mabone a infrared, mass spectrum kapa hydrogen spectrum.

lihlahisoa tse amanang

Boc-D-Dap(Boc).DCHA Boc-Dap(Boc)-OH.DCHA Boc-D-Dap(Fmoc)-OH Boc-Dap(Cbz)-OH
Boc-D-Dap(Cbz)-OH Fmoc-L-Dap(Fmoc)-OH Fmoc-L-Dap(Cbz)-OH Fmoc-D-Dap(cbz)
Cbz-D-Dap(BOC)-OH Cbz-L-Dap(Fmoc)-OH

 

 

Boemo bo phahameng

1. Tshebeletso ya R&D e teng
2. Moetsi ea netefalitsoeng oa ISO, tiiso ea boleng
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  • E fetileng:
  • E 'ngoe:

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