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87512-31-0 Fluorene methoxy carbonyl-L-ALANYL-L-ALANINE

87512-31-0 Fluorene methoxy carbonyl-L-ALANYL-L-ALANINE Featured Image
  • 87512-31-0 Fluorene methoxy carbonyl-L-ALANYL-L-ALANINE
  • 87512-31-0 Fluorene methoxy carbonyl-L-ALANYL-L-ALANINE
  • 87512-31-0 Fluorene methoxy carbonyl-L-ALANYL-L-ALANINE

87512-31-0 Fluorene methoxy carbonyl-L-ALANYL-L-ALANINE

Tlhaloso e Khutšoanyane:

Ponahalo Likristale tse tšoeu ho isa ho tse tšoeu kapa phofo ea crystalline.
MF C21H22N2O5
MW 382.41
Bohloeki 98+


Lintlha tsa Sehlahisoa

Boemo ba lipalangoang&mokhoa oa ho romella o khothalelitsoeng:
?

Boemo ba polokelo:
E koaletsoe sebakeng se omileng, 2-8 ° C

Bonyane Bonyane ba Odara:
Puisano

Setifikeiti:
COA, HPLC, GC, HNMR, Assay, Water Content(KF), TLC e teng

D-Ls(tfa)-NCA (2)

Litlhaloso tse tšoanang

FMOC-ALA-ALA-OH;
Fmoc-L-Ala-L-Ala-OH;
(S)-2-((S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)propanamido)propanoic acid;
Fmoc-Ala-Ala-OH99%;
FMoc-Ala-Ala;
FMOC-ALA-ALA-OH;
FMOC-L-ALANYL-L-ALANINE;
FMoc-AA-OH;
N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-alanyl-L-alanine

Ho paka ka hare

Hangata li sebelisoa ho paka phofo.'Me li ka thibela khanya ea letsatsi le metsi hore li se ke tsa senyeha.

ho phuthela ka ntle

Lebokose le thata le ka sireletsa lihlahisoa tsa hau ho senya le ho koloba.

Lisebelisoa

Sehlahisoa sena ke polypeptide e entsoeng ka li-amino acid tse 28.For N - acetyl - L - silk ammonia acyl - L - alpha amino ammonia acyl - L - propylene ammonia acyl - L - propylene ammonia acyl - L - valerian ammonia acyl - L - alpha amino ammonia acyl - L - Sue ammonia acyl - L wire ammonia acyl - L - wire ammonia acyl - L - alpha glutamine - L - different light ammonia acyl - L - Sue ammonia acyl - L - Sue ammonia acyl - L - lai ammonia acyl - L - alpha amino ammonia acyl - L - e khanyang ammonia acyl - L - lai ammonia acyl - L - alpha - glutamine - L - lai ammonia acyl - L - alpha glutamine - L - valerian ammonia acyl - L - valerian ammonia acyl - L - alpha glutamine - L - alpha - glutamine - L - propylene ammonia veine - L - alpha - glutamine - L - asparagine.Ho ea ka palo ea ntho ea anhydrous le acetic-free, thymus e nang le mokhoa (C129 H215 N33O55) e lokela ho ba 95.0% ~ 105.0%.
Sehlahisoa sena ke phofo e tšoeu kapa e tšoeu kapa boima bo hlephileng.
Sehlahisoa sena se qhibiliha ka trifluoroacetic acid, e qhibilihang hanyane ka metsing, e ke keng ea qhibiliha ka acetonitrile, ether le trichloromethane.
Nka sehlahisoa sena, se lekanya ka nepo, eketsa 0.02mol/L phosphate buffer solution (pH 7.0) (nka 2.72g potassium dihydrogen phosphate, eketsa 0.1mol/L sodium hydroxide solution 116.4ml ho qhala, hlapolla ka metsi ho 1000ml) ebe u etsa tharollo e nang le hoo e ka bang 5mg ho 1ml e 'ngoe le e 'ngoe.E laetsoe ho ea ka molao (Sehlomathiso ⅥE sa Karolo ea II ea Pharmacopoeia, khatiso ea 2010), mokokotlo o khethehileng o lokela ho ba -100.0° ho ea ho -110.0° ho ipapisitsoe le palo ea lintho tse se nang asiti e se nang asiti e se nang anhydrous le acetic.
Mokhoa oa ts'ebetso ea sehlahisoa sena ho phekola lefu la sebete la mofuta oa B le ho matlafatsa ts'ebetso ea 'mele ea ho itšireletsa mafung ha o e-so hlakisoe ka botlalo.Liteko tse ngata tsa in vitro li bonts'itse hore sehlahisoa sena se ka khothaletsa kholo ea T lymphocyte ka ho susumetsa mitogen ea peripheral blood lymphocyte, ho eketsa maemo a interferon α, interferon γ, interleukin 2, interleukin 3 le lintlha tse ling tsa lymphatic tse patiloeng ke lisele tsa T. ka mor'a ts'ebetso ea antigen kapa mitogen, 'me ka nako e ts'oanang eketsa boemo ba li-lymphofactor receptors holim'a lisele tsa T.E ka boela ea ntlafatsa karabelo ea allogeneic le autologous human lymphocyte e tsoakiloeng ka ho kenya tšebetsong lisele tsa CD4.Sehlahisoa sena se ka eketsa ho bokellana ha lisele tsa pele ho NK, 'me interferon e ka eketsa cytotoxicity ea bona.Liteko tsa in vivo li bontšitse hore sehlahisoa sena se ka eketsa boemo ba polelo ea li-receptor tsa interleukin-2 le boemo ba secretion ba interleukin-2 ho li-lymphocyte tsa mouse kamora ts'ebetso ea cancanadin A.

lihlahisoa tse amanang

Gly-Ala-Ome.hcl Fmoc-L-Ala-OH β-Ala-Ome.HCl L-Ala-Phe-OH
Gly-Gly-Ala-Ome.hcl Fmoc-DL-Ala HL-Ala-Ome.Hcl L-Ala-Leu-OH
L-ALA Fmoc-D-Ala-OH β-Ala-Otbu.HCl L-Ala-Pro-OH
DL-ALA Fmoc-β-Ala-OH DL-Ala-Otbu.Hcl DL-Ala-DL-Val
H-Ala-ol Fmoc-LN-Me-Ala-OH L-Ala-NH2.HCl Ala-Gly-Ome.hcl
β-Ala-ol Fmoc-N-Me-D-Ala-OH HD-Ala-NH2·HCl L-Ala-Ala-Obzl.HCl
D-ALA Fmoc-Ala-Cl HD-Ala-NH2 D-Ala-D-Ala-Ome.Hcl
H-β-Ala-OH Fmoc-L-Ala-Ol Ac-L-Ala-NH2 H-Ala-Ala-Otbu.HCL
HN-Me-L-Ala-OH fmoc-β-Ala-NH2 Ac-D-Ala-NH2 Boc-Ala-Phe-OH
HN-Me-D-Ala-OH Fmoc-Ala-Ome AC-D,L-Ala-OH Boc-L-Ala-Leu
L-Ala-NCA Fmoc-Ala-Osu Ac-D-Ala-OH Boc-ALA-Val-OH
D-Ala-NCA fmoc-β-Ala-osu AC-L-Ala-OH Boc-Ala-Pro
L-Ala-nbu.hcl Cbz-L-Ala-OH AC-L-Ala-OME Boc-Ala-Gly-OH
L-Ala-Otbu Cbz-D-Ala-OH Pht-D-Ala Boc-Ala-Ala-OH
D-ALA-Oipr.HCL Cbz-N-Me-L-Ala-OH Pht-L-Ala Boc-Ala-Ala-Ome
D-Ala-Otbu.Hcl Cbz-N-Me-D-Ala-OH Boc-L-Ala-OH Boc-Ala-Ala-Obzl
N-Me-L-Ala-OMe Cbz-DL-Ala-OH Boc-D-Ala-OH Fmoc-Ala-pro
HD-Ala-OBzl·HCl Z-β-L-Ala-OH Boc-DL-Ala-OH Fmoc-Ala-gly-OH
β-Ala-Obzl.Tos Cbz-L-Ala-OL Boc-β-Ala-OH Fmoc-L-Ala-Ala-OH
H-Ala-OBzl·HCl Cbz-L-Ala-NH2 Boc-N-Me-Ala-OH Fmoc-β-Ala-D-phe
HL-Ala-OBzl.Tos-OH Cbz-L-Ala-Ome Boc-N-Me-DL-Ala-OH Fmoc-β-Ala-D-Tyr (Et)
HD-Ala-Oet.HCl Cbz-D-Ala-OMe Boc-N-Me-D-Ala-OH Cbz-Ala-Val-OH
HL-ALA-Oipr.HCL Cbz-Beta-Ala-Ome Boc-L-Ala-Ol Cbz-L-Ala-Ala-OH
N-Me-Ala-Otbu.Hcl Cbz-β-Ala-Otbu Boc-D-Ala-Ol Cbz-Ala-Pro-OH
HL-Ala-OtBu·HCl Cbz-L-Ala-Osu Boc-DL-Ala-Ol Cbz-L-Ala-Leu-OH
H-DL-Ala-OMe.HCl Cbz-Beta-Ala-OSU Boc-Ala-NH2 Cbz-L-Ala-Ala-Ome
β-Ala-Oet.HCl Ala-Ala-OH Boc-D-Ala-NH2 Ala-Ala-Ome.HCL
N-Me-L-Ala-Ome.hcl Ala-gly Boc-β-Ala-NH2 Val-Ala
HD-Ala-Ome.Hcl L-ALA-Val-OH Boc-D-4-Chloropheny(alanine) Boc-Ala-Pro
Boc-L-ALA-OBZL Boc-Leu-Ala Boc-D-3(1-Naphthgl)-alanine Boc-Val-Ala
Boc-L-Ala-OSu Fmoc-leu-ala Boc-L-Ala-Ome Cbz-Val-Ala-OH
Boc-L-Beta-Ala-Osu Cbz-Leu-Ala-OH Boc-D-Ala-OMe Cbz-Val-Ala-Ome
Boc-D-Ala-OSu Phe-Ala Boc-L-Ala-Otbu Leu-Ala-OH
Fmoc-L-Ala-OH.H2O Boc-Phe-Ala-OH Z-Lys(boc)-Ala-Ala-OBzl HL-Thr-OBzl·oxalate
HL-Thr(Bzl)-OBzl.oxalate Cbz-Phe-Ala-OH  

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