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40216-83-9 H-Hyp-Ome·HCl

40216-83-9 H-Hyp-Ome·HCl

Tlhaloso e Khutšoanyane:

Ponahalo Phofo e tšoeu
MF C6H12ClNO3
MW 181.62
Bohloeki 98+


Lintlha tsa Sehlahisoa

Boemo ba lipalangoang
E ka ba mocheso o tloaelehileng

Khothalletsa mokhoa oa ho romella
Ka moea Ka naha Ka leoatle

Boemo ba polokelo:
Lula sebakeng se lefifi, sepakapaka se se nang moea, mocheso oa kamore

Shelf bophelo
Hoo e ka bang lilemo tse 2

Bonyane Odara Qty:
1kg (puisano)

Setifikeiti:COA, ntlha e qhibidihang, SpecificRotation [α]D20                      

Re tla romella data efe kapa efe eo u e batlang.U ka bona data pele e le litšupiso.

Bakeng sa lihlahisoa tse ikhethileng, re romella lintlha tse ncha ka mor'a hore li tsoe.

D-Ls(tfa)-NCA (2)

Litlhaloso tse tšoanang

H-HYP-OMEHCL;
HL-HYP-OMEHCL;
HYDROXYPROLINE-OMEHCL;
(2S, 4R) -trans-4-hydroxy-L-prolinemethylesterhydrochloride;
4-hydroxy-2-pyrrolidinecarboxylicacidmethylesterhydrochloride;
L-4-HYDROXYPROLINEMETHYLESTERHYDROCHLORIDE;
L-4-HYDROXYPROLINEMETHYLESTERHYDROCHLORIDESALT;
L-4-TRANS-HYDROXYPROLINEMETHYLESTERHYDROCHLORIDE

Ho paka ka hare

Hangata li sebelisetsoa ho paka phofo.E itšetlehile ka litlhoko tsa bareki.Ka hona, re bolelle seo u se batlang pele u paka haeba u na le likopo tse khethehileng.

Ho paka ka hare 2
Ho paka ka hare 1
Ho paka ka hare 3

ho phuthela ka ntle

1kg ho isa ho 25kg Ho paka ka ntle ho thata.'Me ho thata ho khaola le ho senya.E ka sireletsa lihlahisoa tsa hau ka ho phethahetseng.

Ho paka ka ntle 3
Ho paka ka ntle 2
Ho paka ka ntle 1

Lisebelisoa

Lisebelisoa: H-Hyp-OMe·HCl e sebetsa e le sehokelo sa ADC se sa hlakoheng (antibody-drug conjugate) bakeng sa motsoako oa ADCs.Li-ADC, tse entsoeng ka antibody le cytotoxin e hokahantsoeng ka sehokelo sa ADC, li thusa ho fana ka li-cytotoxin ka nepo liseleng tse lebisitsoeng, kahoo li phekola mafu a itseng.Ho feta moo, H-Hyp-OMe·HCl ke PROTAC (protheine degradation targeting chimera) sehokelo se thehiloeng ho liketane tsa alkyl, tse sebelisoang ha ho etsoa li-PROTAC.Li-PROTAC, tse nang le li-ligand tse peli tse ikhethileng tse hokahaneng le sehokelo, li sebelisa sistimi ea ubiquitin-proteasome ea cellular ho nyenyefatsa liprotheine tse lebisitsoeng.

Thepa: H-Hyp-OMe·HCl ke phofo ea amorphous e tšoeu kapa e mosehla hanyenyane 'me e qhibiliha ka har'a metsoako e kang metsi, methanol le ethanol.E bonts'a botsitso bo botle le biocompatibility, ho boloka ts'ebetso ea eona le botsitso tlasa maemo a fisioloji.

Ka kakaretso, H-Hyp-OMe·HCl e bapala karolo ea bohlokoa ho kopanngoeng ha ADC le PROTAC e le sesebelisoa sa bohlokoa sa biochemical reagent le sesebelisoa sa ntlafatso ea lithethefatsi.E fana ka mekhoa le mekhoa e mecha ea ho phekola mafu.Ha lipatlisiso li ntse li tsoela pele le theknoloji e fetoha, menyetla ea ts'ebeliso ea H-Hyp-OMe·HCl e lebelletsoe ho hola.

lihlahisoa tse amanang

L-Hyp-OH HL-Hyp-Ome·HCl
HL-Hyp-Oet.HCl L-Hyp-Obzl.Hcl
Boc-L-Hyp-OH Boc-L-Hyp-Ome
Fmoc-L-Hyp-Ome Boc-L-Hyp-oet
Fmoc-L-Hyp-OH Fmoc-L-Hyp(tbu)-OH
Cbz-L-Hyp-OH Cbz-L-Hyp-OMe

Boemo bo phahameng

1. Re fana ka ho iketsetsa lihlahisoa tseo u li hlokang.
2. Boleng bo phahameng & theko ea tlhōlisano e ka fanoa.
3. Re ts'episa ts'ebeletso e felletseng ea ts'ebeletso bakeng sa hau.
4. Lenane la lipotso tsa bafani le litokomane tsa tekheniki li ka fanoa haeba li kopa ka mor'a ho kopana le chelete e itseng.
5. Tšebeletso e ntle ka mor'a thekiso kapa tiisetso : Potso efe kapa efe ea hau e ka rarolloa kapele kamoo ho ka khonehang.
6. Romela dihlahiswa tsa tlhodisano kantle ho naha le ho di romela kantle ho naha ka bongata bo boholo selemo se seng le se seng.
7. Free sampole e filwe ho hlahloba tsoa boleng pele ho tefo efe kapa efe.


  • E fetileng:
  • E 'ngoe:

  • Ngola molaetsa wa hao mona mme o re romele wona