China 2013-12-9 D(-)-Norvaline Moetsi le Fektheri |Jiayinglai

2013-12-9 D(-)-Norvaline

Tlhaloso e Khutšoanyane:

Ponahalo	Bosoeu ho isa ho bosoeu
MF	C5H11NO2
MW	117.15
Bohloeki	98+

Re romelle lengolo-tsoibila

Lintlha tsa Sehlahisoa

Boemo ba lipalangoang&mokhoa oa ho romella o khothalelitsoeng:
ka moya, ka lewatle kapa ka polelo

Boemo ba polokelo:
2-8°C

Bonyane Bonyane ba Odara:
Puisano

Setifikeiti:
COA, HPLC, GC, HNMR, Assay, Water Content(KF), TLC e teng

Litlhaloso tse tšoanang

HD-NVA-OH;

HD-NHCH[CH3(CH2)2]-COOH;

HD-NORVALINE;

HD-APE(2)-OH;

D-Nval-OH;

HD-2-AMINOVALERIC ACID;

D-Nva-OH;

D-Nval

Ho paka ka hare

Hangata li sebelisoa ho paka phofo.'Me li ka thibela khanya ea letsatsi le metsi hore li se ke tsa senyeha.

ho phuthela ka ntle

Lebokose le thata le ka sireletsa lihlahisoa tsa hau ho senya le ho koloba.

Lisebelisoa

E ka sebelisoa ho etsa D-Glu.Mefuta e fapaneng ea d-aminoacids, joalo ka D-serine, D-aspartic acid (D-Asp), le D-glutamicacid (D-Glu) e fumaneha haholo liphoofolong tse anyesang ho kenyeletsoa le batho, 'me joale ho nahanoa hore ke bona ba khethiloeng bukeng ea physiologically active. lintho le/kapa biomarker.D-[Asp/Glu](4mg/mL) e thibela ho tlama ha IgE (75%) ho matokomane ha D-Glu, D-Asp e se na phello e thibelang.IgE e tobane le D-[Asp/Glu] mme e kanna ea ba le monyetla oa ho tlosa IgE kapa ho fokotsa ho tlama ha IgE ho lintho tse amanang le peanut.

D-glutamicacid hajoale e lebisitsoe tlhokomelong e le modulator ea phetiso ea methapo ea kutlo le secretion ea lihormone.E sebelisoa feela ke D-aspartate oxidase ho liphoofolo tse anyesang.Kamora ente ea intraperitoneal, L-glutamate e ts'oaroa ka a-ketoglutarate, athe D-glutamate e fetoloa ho n-pyrrolidone carboxylic acid.Carbon2 ea D- le L-glutamate ka bobeli e fetoloa ka har'a cecum ho ea methyl carbon ea acetate.Ka bobeli sebete sa rat le liphio li susumetsa phetoho ea D-glutamicacid ho n-pyrrolidone carboxylic acid.

lihlahisoa tse amanang

L-Nval-OH	Fmoc-N-Me-L-Nval-OH
Fmoc-D-NvaL-OH	Boc-Nval-OH
Boc-D-Nval-OH	Boc-D-Nval-DCHA

Boemo bo phahameng

1. Tshebeletso ya R&D e teng
2. Moetsi ea netefalitsoeng oa ISO, tiiso ea boleng
3.Tsamaiso e feletseng ea ts'ebeletso ea ho latela nakong ea tlhahiso
4.Chelete e phahameng e atlehang
5.Litokomane tsa setifikeiti sa boleng tse fanoeng ho latela kopo ea moreki
Tšebeletso ea 6.E kholo ka mor'a thekiso, ho boloka kamano e haufi le moreki
7.Mohloli o felletseng oa ho thusa ho fokotsa litšenyehelo tsa ho tsamaisa thepa
8.Free sampole e filwe ho hlahloba tsoa boleng pele ho tefo efe kapa efe
9.Ho buisanoa ka nako ea tefo
Bareki ba 10.Assit ba sebetsana le litaba tsa China