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1799443-50-7 Fmoc-N-Me-D-Tyr(tBu)-OH

1799443-50-7 Fmoc-N-Me-D-Tyr(tBu)-OH

Tlhaloso e Khutšoanyane:

Ponahalo phofshoana e tšoeu
MF C29H31NO5
MW 473.56
Bohloeki 98+


Lintlha tsa Sehlahisoa

Boemo ba lipalangoang
E ka ba mocheso o tloaelehileng

Khothalletsa mokhoa oa ho romella
Ka moea Ka naha Ka leoatle

Boemo ba polokelo:
Lula sebakeng se lefifi, sepakapaka se se nang moea, mocheso oa kamore

Shelf bophelo
Hoo e ka bang lilemo tse 2

Bonyane Bonyane oa Odara:
1kg (puisano)

Setifikeiti:COA, ntlha e qhibidihang, SpecificRotation [α]D20                      

Re tla romella data efe kapa efe eo u e batlang.U ka bona data pele e le litšupiso.

Bakeng sa lihlahisoa tse ikhethileng, re romella lintlha tse ncha ka mor'a hore li tsoe.

D-Ls(tfa)-NCA (2)

Litlhaloso tse tšoanang

(R) -2-((((9H-Fluoren-9-yl)methoxy)carbonyl)(methyl)amino)-3-(4-(tert-butoxy)phenyl)propanoicacid;

(9H-Fluoren-9-yl)MethOxy]CarbonylN-Me-D-Tyr(tBu)-OH;

(2R) -3-[4-(tert-butoxy)phenyl] -2-({[(9H-fluoren-9-yl)methoxy]carbonyl}(methyl)amino)propanoicacid;

(2R) -2- [9H-fluoren-9-ylmethoxycarbonyl(methyl) amino]-3- [4- [(2-methylpropan-2-yl) oxy]phenyl]propanoicacid;

N-Fmoc-N-methyl-O-tert-butyl-D-tyrosine;

D-Tyrosine,O-(1,1-dimethylethyl)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-N-methyl-

Ho paka ka hare

Hangata li sebelisetsoa ho paka phofo.E itšetlehile ka litlhoko tsa bareki.Ka hona, re bolelle seo u se batlang pele u paka haeba u na le likopo tse khethehileng.

Ho paka ka hare 2
Ho paka ka hare 1
Ho paka ka hare 3

ho phuthela ka ntle

1kg ho isa ho 25kg Ho paka ka ntle ho thata.'Me ho thata ho khaola le ho senya.E ka sireletsa lihlahisoa tsa hau ka ho phethahetseng.

Ho paka ka ntle 3
Ho paka ka ntle 2
Ho paka ka ntle 1

Lisebelisoa

Fmoc-N-Me-D-Tyr(TBu)-OH, e tsejoang hape e le N-α-(9-fluorenylmethoxycarbonyl)-N-α-methyl-D-tyrosine tert-butyl ester, ke motsoako o sirelelitsoeng oa amino acid o sebelisoang hangata. ka sebopeho sa peptide e tiileng.Motsoako ona o kopanya sehlopha sa tšireletso sa Fmoc bakeng sa amino terminus e nang le tert-butyl (TBu) ester e sireletsang sehlopha sa phenolic hydroxyl sa D-tyrosine.

Sehlopha sa Fmoc, joalo ka ha ho boletsoe pejana, se tsitsitse ebile se qhibiliha ka har'a metsoako ea lintho tse hlapollang, se etsa hore se tšoanelehe bakeng sa motsoako oa peptide.E ka tlosoa habonolo tlas'a maemo a alkaline, e lumellang kopano e latellanang ea li-peptide holim'a litšehetso tse tiileng.Ka lehlakoreng le leng, tert-butyl ester e sireletsa sehlopha sa phenolic hydroxyl ea D-tyrosine, ho netefatsa botsitso le bohloeki ba eona nakong ea ts'ebetso ea ho kopanya.

Tšebeliso e ka sehloohong ea Fmoc-N-Me-D-Tyr(TBu)-OH ke ho lokisetsa li-peptide tse nang le D-tyrosine.Ka ho sebelisa motsoako ona oa amino acid, bafuputsi ba ka hlahisa D-tyrosine ka lihlopha tsa amino le phenolic hydroxyl tse sirelelitsoeng tatellanong ea tsona ea peptide.Sena se fana ka taolo e nepahetseng holim'a sebopeho sa peptide mme se thusa ho hlahisoa ha li-amino acid tse ling le liphetoho maemong a ikhethileng ka har'a ketane ea peptide.

D-Tyrosine ke amino acid eo e seng ea tlhaho e ka kenyelletsoang ho li-peptide ho ithuta thepa ea bona ea tlhaho kapa ho etsa li-analogue tsa peptide tse nang le mesebetsi e fetotsoeng.Li-peptide tse nang le D-tyrosine li ka ba le mesebetsi e fapaneng ea likokoana-hloko ha li bapisoa le balekane ba tsona ba L-tyrosine, ka lebaka la phapang ea stereochemical pakeng tsa li-amino acid tse peli.

lihlahisoa tse amanang

N-Me-Tyr(Me)-OH.HCl Boc-N-Me-L-Tyr(tbu)-OH Fmoc-N-Me-L-Tyr(tBu)-OH Cbz-N-Me-Tyr(tbu)-OH
FMOC-N-Me-D-Tyr(me)-OH Boc-N-Me-L-Tyr(bzl)-OH Fmoc-N-Me-L-Tyr(bzl)-OH Boc-N-Me-D-Tyr(bzl)-OH

Ke Hobane'ng ha U Re Khetha

1. Mabapi le MOQ: Re ka e fetola ho latela tlhoko ea hau.
2. Mabapi le mohlala: Mohlala o hloka tefiso ea mohlala, e ka ba thepa ea ho bokella kapa u ka e lefa esale pele.
3. Mold workshop, e ka etsoa customized ho ea ka palo ea mehlala.
4. Re fana ka tšebeletso e molemohali.Sehlopha sa barekisi se nang le boiphihlelo se se se ntse se u sebeletsa.
5. Mabapi le phapanyetsano: Ka kopo romella lengolo-tsoibila kapa u qoqa le 'na ha u le bonolo.


  • E fetileng:
  • E 'ngoe:

  • Ngola molaetsa wa hao mona mme o re romele wona