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166108-71-0 Fmoc-AEEA-OH

166108-71-0 Fmoc-AEEA-OH

Tlhaloso e Khutšoanyane:

Ponahalo Phofo e tšoeu ho isa ho e tšoeu
MF C21H23NO6
MW 385.41
Bohloeki 98+


Lintlha tsa Sehlahisoa

Boemo ba lipalangoang
E ka ba mocheso o tloaelehileng

Khothalletsa mokhoa oa ho romella
Ka moea Ka naha Ka leoatle

Boemo ba polokelo:
Lula sebakeng se lefifi, sepakapaka se se nang moea, mocheso oa kamore

bophelo ba raka
Hoo e ka bang lilemo tse 2

Bonyane Bonyane oa Odara:
1kg (puisano)

Setifikeiti:COA, ntlha e qhibidihang, SpecificRotation [α]D20                      

Re tla romella data efe kapa efe eo u e batlang.U ka bona data pele e le litšupiso.

Bakeng sa lihlahisoa tse ikhethileng, re romella lintlha tse ncha ka mor'a hore li tsoe.

D-Ls(tfa)-NCA (2)

Litlhaloso tse tšoanang

[2- [2-(Fmoc-amino) ethoxy]ethoxy]acetic acid

Fmoc-8-amino-3,6-dioxaoctanoic acid, Fmoc-AEEA

Fmoc-PEG2-acetic acid

{2-[2-(Fmoc-amino)ethoxy]ethoxy}acetic acid≥ 99% (HPLC)

Fmoc-NH-(PEG)-COOH (9 liathomo) Novabiochem

1-(9H-Fluoren-9-yl)-3-oxo-2,7,1-trioxa-4-azadodecan-12-oic acid

9-FLUORENYLMETHOXYCARBONYL-8-AMINO-3,6-DIOXAOCTANOIC ACID

8-(FMOC-AMINO) -3,6-DIOXA-OCTANOIC ACID

8-FLUORENYLMETHOXYCARBONYLAMINO-3,6-DIOXAOCTANOIC ACID

Ho paka ka hare

Hangata li sebelisetsoa ho paka phofo.E itšetlehile ka litlhoko tsa bareki.Ka hona, re bolelle seo u se batlang pele u paka haeba u na le likopo tse khethehileng.

Ho paka ka hare 2
Ho paka ka hare 1
Ho paka ka hare 3

ho phuthela ka ntle

1kg ho isa ho 25kg Ho paka ka ntle ho thata.'Me ho thata ho khaola le ho senya.E ka sireletsa lihlahisoa tsa hau ka ho phethahetseng.

Ho paka ka ntle 3
Ho paka ka ntle 2
Ho paka ka ntle 1

Lisebelisoa

166108-71-0 Fmoc-AEEA-OH ke sehokelo sa ADC se ka phunyehang se sebelisoang ha ho etsoa li-antibody-drug conjugates (ADCs).Fmoc-8-amino-3,6-dioxaoctanoic acid hape ke PEG-based PROTAC linker e ka sebelisoang ha ho etsoa li-PROTAC.

166108-71-0 Fmoc-AEEA-OH hape e ka ba e 'ngoe ea Semaglutide Intermediates.

Phello e kholo ea semaglutide ke ho phekola lefu la tsoekere la mofuta oa 2 ka ho theola maemo a tsoekere ea mali.E etsisa insulin-joaloka peptide-1 hormone, e susumetsang tlhahiso ea insulin le ho thibela ho lokolloa ha glucagon, kahoo e theola boemo ba tsoekere maling.Semaglutide ha e kenye letsoho kotsing ea hypoglycemia e hlahang ha e bapisoa le kalafo e tloaelehileng ea insulin hobane mokhoa oa eona oa ts'ebetso o rarahane ebile o nepahetse.Ka ho fetola tekanyo ea insulin le glucagon, somalitide e ka thusa batho ba nang le lefu la tsoekere la mofuta oa 2 ho laola maemo a tsoekere ea mali.

Ntle le ho fokotsa maemo a tsoekere ea mali, semaglutide e ka boela ea fokotsa boima ba 'mele.Sena se bakoa ke phello ea eona ea ho hatella takatso ea lijo.semaglutide e susumetsa mosebetsi oa setsi sa satiety ho hypothalamus, e fokotsang takatso ea lijo.Molemo o ka sehloohong oa semaglutide holim'a lithethefatsi tse ling tsa tahlehelo ea boima ba 'mele ke hore e theola boima ba' mele ha e ntse e ntlafatsa ho hanyetsa insulin le ho laola tsoekere ea mali.Sena se etsa hore e be khetho e lakatsehang haholo ea kalafo ho bakuli ba nang le lefu la tsoekere ba nang le botenya.

Ho feta moo, semaglutide e ntlafatsa ts'ebetso ea pancreatic mme e fokotsa likarabo tsa ho ruruha liseleng tsa pancreatic islet.E sireletsa lisele tsa islet tšenyo e eketsehileng e bakoang ke lefu la tsoekere 'me e khothalletsa ho tsosolosoa ha lisele tsa islet.Sena se bohlokoa haholo ho batho ba nang le lefu la tsoekere la mofuta oa 2, kaha tšenyo e ngata haholo ea lisele tsa islet e ka baka ho hloleha ha lihlekehleke.

Ka kakaretso, semaglutide ke meriana e sebetsang haholo le e sireletsehileng bakeng sa phekolo ea lefu la tsoekere la mofuta oa 2.E thusa bakuli ho laola lefu la tsoekere hantle le ho fokotsa mathata ka ho theola maemo a tsoekere ea mali, ho fokotsa boima ba 'mele, ho ntlafatsa ts'ebetso ea lihlekehleke, le ho sireletsa lisele tsa islet.Lithuto tsa nakong e tlang li tla tsoela pele ho hlahloba bokhoni ba somatostatin ho phekola mafu a mang, a kang NAFLD le botenya.

lihlahisoa tse amanang

Fmoc-AEEA-AEEA-OH Fmoc-L-Lys(dde)-OH DDE-Ls(Fmoc)-OH

Ke Hobane'ng ha U Re Khetha

1. Mabapi le MOQ: Re ka e fetola ho latela tlhoko ea hau.
2. Mabapi le mohlala: Mohlala o hloka tefiso ea mohlala, e ka ba thepa ea ho bokella kapa u ka e lefa esale pele.
3. Mold workshop, e ka etsoa customized ho ea ka palo ea mehlala.
4. Re fana ka tšebeletso e molemohali.Sehlopha sa barekisi se nang le boiphihlelo se se se ntse se u sebeletsa.
5. Mabapi le phapanyetsano: Ka kopo romella lengolo-tsoibila kapa u qoqa le 'na ha u le bonolo.


  • E fetileng:
  • E 'ngoe:

  • Ngola molaetsa wa hao mona mme o re romele wona