103898-11-9 Tert-Butyl N,N-Bis(2-Hydroxyethyl)Carbamate

Ho sibolla Lithethefatsi: Tert-Butyl N,N-Bis(2-Hydroxyethyl)Carbamate hangata e sebelisoa e le sehlopha se sireletsang tšibollong ea lithethefatsi.E sebetsana le lihlopha tse sebetsang joalo ka li-hydroxyls le li-amine ka har'a limolek'hule tsa lithethefatsi, ho etsa tse ling tse sirelelitsoeng tsa tert-butoxycarbonyl (Boc).Tšireletso ena e lumella hore ho be le motsoako o tsitsitseng le ho hloekisoa, 'me sehlopha sa Boc se ka tlosoa tlas'a maemo a loketseng ho pepesa sehlopha sa pele se sebetsang bakeng sa karabelo e eketsehileng kapa lithuto tsa likokoana-hloko.Ka hona, e na le ts'ebeliso e ka bang teng ts'ebetsong ea litlhare, phetoho ea lithethefatsi, le tokollo e laoloang ea lithethefatsi.

Peptide Synthesis: Tert-Butyl N,N-Bis(2-Hydroxyethyl)Carbamate e boetse e fumana tšebeliso e le sehokelo ho motsoako oa peptide.E ka sebetsana le sehlopha sa carboxyl sa li-amino acid, ho etsa li-amide tse tsitsitseng ho hokahanya li-amino acid tse peli kapa ho feta, ho theha liketane tsa peptide tse nang le tatellano le mekhoa e itseng.Sehokelo sena se sebelisoa haholo ho synthesis ea peptide ea mokhahlelo o tiileng, motsoako oa lipeptide tsa mokelikeli le mekhoa e meng.

Patlisiso ea Lik'hemik'hale: Ka lebaka la tlhaho ea eona e ka senyehang, Tert-Butyl N,N-Bis(2-Hydroxyethyl)Carbamate e boetse e sebelisoa e le sesebelisoa lipatlisisong tsa biochemical.Ka mohlala, e ka sebelisoa e le sehokahanyo ha ho etsoa li-antibody-drug conjugates (ADCs), ho hokahanya lithethefatsi le li-antibodies bakeng sa ho fana le ho lokolloa.Ho feta moo, e ka sebelisoa ho ithuta litšebelisano tsa protheine-protein le protheine-ligand, hammoho le ts'ebetso ea protheine le ho sebetsa ka har'a lisele.